Grimelius kit is used in histology for visualisation of argyrophilic structures in histology tissue sections. Certain tissues, such as neuroendocrine tumours can bind to silver ions from silver nitrate solution, but not reduce them to the visible form – elementary silver; this is why silver ion reduction during staining is achieved by exposing the section to the reducing hydroquinone solution and sodium sulfite. Excessive unbound silver ions are removed by rinsing the section with the sodium thiosulfate solution.
Grimelius kit
Five-reagent kit for staining argyrophilic granules. Grimelius kit can be used for the detection of secretory intracytoplasmatic granules specific for carcinoid tumours and for identification of neuroendocrine cells.
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Additional information
| Size | |
|---|---|
| Brand | |
| Stain pack | |
| Stain Category | Pigments and Mineral Deposits |
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